STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1149351aa long hypothetical X-Pro dipeptidase; Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position. (351 aa)    
Predicted Functional Partners:
PH0628
295aa long hypothetical methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
 
  
 0.845
PH1013
162aa long hypothetical protein.
   
 
 0.763
PH1830
334aa long hypothetical glyceraldehyde-3-phosphate dehydrogenase; Similar to Swiss_Prot:P20286 percent identity: 90.719 in 334aa; Swiss_Prot:P10618 percent identity: 56.061 in 334aa; Swiss_Prot:P19315 percent identity: 57.751 in 335aa. motif=glyceraldehyde 3-phosphate dehydrogenase active site.
   
 
 0.728
PH1151
307aa long hypothetical sulfatase; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
     
 0.649
PH0240
449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
    0.610
PH1150
236aa long hypothetical arylmalonate decarboxylase; Similar to owl:SLTRNGL percent identity:31.288 in 164aa; Swiss_Prot:Q05115 percent identity:28.910 in 214aa.
       0.580
PH1152
223aa long hypothetical protein; Similar to PIR:D64470 percent identity:37.688 in 216aa.
       0.548
PH0307
486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.457
PH0290
431aa long hypothetical histidyl-tRNA synthetase; Similar to PIR:G64424 percent identity: 45.854 in 425aa; owl:HPAE0006251 percent identity: 33.577 in 418aa; Swiss_Prot:P46220 percent identity: 46.617 in 133aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.434
PH1381
138aa long hypothetical translation initiation factor eIF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.422
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.