STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1157265aa long hypothetical protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (265 aa)    
Predicted Functional Partners:
PH1155
446aa long hypothetical thiamine biosynthesis protein; Similar to Swiss_Prot:P44697 percent identity: 51.538 in 267aa; owl:HPAE0005959 percent identity: 44.531 in 262aa; owl:MTCY22G1018 percent identity: 44.980 in 254aa.
 
 
 0.999
PH1156
161aa long hypothetical thiamine biosynthetic bifunctional protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
PH1161
218aa long hypothetical transcriptional regulator; Similar to owl:HPAE0006332 percent identity:31.604 in 217aa; Swiss_Prot:P44659 percent identity:27.451 in 208aa; Swiss_Prot:P25052 percent identity:26.442 in 211aa.
  
 
 0.952
PH1921
301aa long hypothetical tryptophanyl-tRNA synthetase; Similar to owl:S51901 percent identity: 49.296 in 298aa; Swiss_Prot:Q09692 percent identity: 48.352 in 286aa; Swiss_Prot:P23381 percent identity: 46.831 in 301aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
      0.736
PH1159
422aa long hypothetical cytosine permease; Similar to Swiss_Prot:P25525 percent identity:26.149 in 351aa.
  
    0.655
PH1160
211aa long hypothetical protein; Similar to owl:HPAE0006332 percent identity:27.451 in 212aa; Swiss_Prot:P44659 percent identity:19.403 in 208aa.
  
  
 0.543
PH1833
309aa long hypothetical protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
     
 0.492
PH1349
347aa long hypothetical thiamin-binding periplasmic protein precursor; Similar to Swiss_Prot:P31550 percent identity: 37.367 in 289aa; Swiss_Prot:P44984 percent identity: 36.131 in 284aa. motif=prokaryotic membrane lipoprotein lipid attachment site.
  
  
 0.484
PH0056
230aa long hypothetical HESA protein; Similar to Swiss_Prot:P46048 percent identity: 44.037 in 223aa; Swiss_Prot:P18500 percent identity: 41.872 in 206aa; PIR:A49890 percent identity: 39.450 in 223aa.
  
  
 0.456
PH0314
896aa long hypothetical valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
      
 0.422
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.