STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1218410aa long hypothetical phosphoglycerate kinase; Similar to Swiss_Prot:P50316 percent identity: 77.995 in 409aa; PIR:A64380 percent identity: 50.125 in 413aa; Swiss_Prot:P20971 percent identity: 44.275 in 401aa. motif=phosphoglycerate kinase signature. (410 aa)    
Predicted Functional Partners:
PH1830
334aa long hypothetical glyceraldehyde-3-phosphate dehydrogenase; Similar to Swiss_Prot:P20286 percent identity: 90.719 in 334aa; Swiss_Prot:P10618 percent identity: 56.061 in 334aa; Swiss_Prot:P19315 percent identity: 57.751 in 335aa. motif=glyceraldehyde 3-phosphate dehydrogenase active site.
 0.999
PH1884
231aa long hypothetical triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.987
PH1942
428aa long hypothetical phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.967
PH1630
341aa long hypothetical protein.
 
 
 0.959
PH0037
412aa long hypothetical phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.928
PH0457
653aa long hypothetical protein; Similar to PIR:H64447 percent identity: 48.739 in 631aa. motif=crystallins beta and gamma 'Greek key' motif signature; eukaryotic thiol (cysteine) proteases active sites.
 
  
 0.923
PH0570
478aa long hypothetical pyruvate kinase; Similar to PIR:A57418 percent identity:76.037 in 217aa; PIR:S76677 percent identity:42.128 in 484aa; Swiss_Prot:Q02499 percent identity:43.991 in 475aa. motif=eukaryotic thiol (cysteine) proteases active sites; Belongs to the pyruvate kinase family.
 
 
 0.858
PH1217
216aa long hypothetical alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.793
PH1219
423aa long hypothetical protein; motif=CDP-alcohol phosphatidyltransferases signature; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.773
PH1220
117aa long hypothetical protein.
       0.773
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.