node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PH0307 | PH0852 | gene:9377224 | gene:9377803 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 0.962 |
PH0307 | PH1346 | gene:9377224 | gene:9378322 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.992 |
PH0307 | PH1347 | gene:9377224 | gene:9378323 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 308aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
PH0307 | PH1478 | gene:9377224 | gene:9378456 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature. | 0.479 |
PH0307 | PH1691 | gene:9377224 | gene:9378685 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 256aa long hypothetical protein. | 0.610 |
PH0307 | PH1792 | gene:9377224 | gene:9378794 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 557aa long hypothetical CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.800 |
PH0307 | PH1917 | gene:9377224 | gene:9378927 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 186aa long hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.948 |
PH0307 | PH1953 | gene:9377224 | gene:9378966 | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 705aa long hypothetical phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.759 |
PH0852 | PH0307 | gene:9377803 | gene:9377224 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.962 |
PH0852 | PH1346 | gene:9377803 | gene:9378322 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.813 |
PH0852 | PH1347 | gene:9377803 | gene:9378323 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 308aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.933 |
PH0852 | PH1478 | gene:9377803 | gene:9378456 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature. | 0.583 |
PH0852 | PH1691 | gene:9377803 | gene:9378685 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 256aa long hypothetical protein. | 0.789 |
PH0852 | PH1792 | gene:9377803 | gene:9378794 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 557aa long hypothetical CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.585 |
PH0852 | PH1917 | gene:9377803 | gene:9378927 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 186aa long hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.414 |
PH0852 | PH1953 | gene:9377803 | gene:9378966 | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 705aa long hypothetical phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.992 |
PH1346 | PH0307 | gene:9378322 | gene:9377224 | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 486aa long hypothetical inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.992 |
PH1346 | PH0852 | gene:9378322 | gene:9377803 | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 0.813 |
PH1346 | PH1347 | gene:9378322 | gene:9378323 | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 308aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
PH1346 | PH1354 | gene:9378322 | gene:9378330 | 189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 196aa long hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.977 |