STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1355335aa long hypothetical ethylene-responsive protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa)    
Predicted Functional Partners:
PH1354
196aa long hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
PH1346
189aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.978
PH1347
308aa long hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.924
PH1923
287aa long hypothetical ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
   
 
  0.807
PH1375
229aa long hypothetical ribose 5-phosphate isomerase; Involved in the first step of the non-oxidative branch of the pentose phosphate pathway. It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
  0.801
PH0923
455aa long hypothetical phospho-sugar mutase; Similar to PIR:C64437 percent identity: 41.839 in 455aa; owl:SAFEMD percent identity: 34.259 in 445aa; owl:SAURED percent identity: 34.259 in 445aa. motif=prokaryotic membrane lipoprotein lipid attachment site.
     
  0.800
PH1512
837aa long hypothetical protein; Similar to Swiss_Prot:Q10639 percent identity: 39.944 in 751aa. motif=phosphorylase pyridoxal-phosphate attachment site.
      
 0.750
PH0655
348aa long hypothetical dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate. Is much less efficient when using NADP(+) instead of NAD(+). To a lesser extent, also catalyzes the oxidation of L-serine and DL-threo-3- phenylserine, but not that of L-allo-threonine, D-threonine and D-allo- threonine and many other L-amino acids.
   
  
 0.656
PH0795
105aa long hypothetical protein; Similar to PIR:B64411 percent identity:43.038 in 80aa; Belongs to the UPF0148 family.
      
 0.647
PH1533
133aa long hypothetical protein; Motif=aldehyde dehydrogenases active sites.
      
 0.647
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.