STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1402207aa long hypothetical proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (207 aa)    
Predicted Functional Partners:
PH1553
260aa long hypothetical proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.938
PH0245
197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
  
 
0.904
PH0201
399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...]
  
 0.899
PH0127
126aa long hypothetical protein; Similar to PIR:A64313 percent identity:32.673 in 103aa.
      
 0.769
PH0451
122aa long hypothetical protein.
   
 0.638
PH1488
170aa long hypothetical protein.
   
 0.638
PH0017
549aa long hypothetical thermophilic factor; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
 
 
 0.637
PHS037
51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.609
PH1401
203aa long hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
       0.551
PH0687
840aa long hypothetical cell division control protein (transitional endoplasmic reticulum ATPase); Similar to PIR:C64444 percent identity: 68.554 in 760aa; Swiss_Prot:Q07590 percent identity: 62.391 in 771aa; owl:TAU78072 percent identity: 61.891 in 761aa. motif=AAA-protein family signature; ATP/GTP-binding site motif A (P-loop).
  
 0.548
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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