STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1421231aa long hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate (By similarity). Has phosphatase activity towards p-nitrophenylphosphate (in vitro); Belongs to the archaeal SPP-like hydrolase family. (231 aa)    
Predicted Functional Partners:
PH0597
376aa long hypothetical dehydrogenase; Similar to owl:BSZ9404317 percent identity: 49.821 in 287aa; Swiss_Prot:P37666 percent identity: 43.750 in 327aa; PIR:A64427 percent identity: 42.633 in 330aa. motif=ATP/GTP-binding site motif A (P-loop); D-isomer specific 2-hydroxyacid dehydrogenases s.
  
 
 0.923
PH0939
430aa long hypothetical ribulose 1,5-bisphosphate carboxylase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
  0.901
PH1422
218aa long hypothetical protein.
       0.773
PH1771
127aa long hypothetical protein; Part of ribonuclease P (RNase P), a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Binds RNase P RNA.
  
   
 0.705
PH0749
230aa long hypothetical protein.
  
  
 0.509
PH1691
256aa long hypothetical protein.
  
  
 0.497
PH1496
124aa long hypothetical 50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). When added to reconstituted ribonuclease P (RNase P) it increases the optimum temperature to that of the partially purified enzyme and causes a 5-fold increase in apparent Vmax. Binds the RNase P catalytic RNA.
  
   0.494
PH1416
330aa long hypothetical protein; Similar to PIR:C64410 percent identity: 45.625 in 343aa; PIR:D64494 percent identity: 40.097 in 212aa.
       0.484
PH1418
143aa long hypothetical protein.
       0.484
PH1419
114aa long hypothetical protein.
       0.484
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.