STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1426336aa long hypothetical thioredoxin reductase; Similar to owl:BSZ940436 percent identity: 51.656 in 315aa; owl:AF0096221 percent identity: 49.667 in 313aa; Swiss_Prot:P50971 percent identity: 46.154 in 316aa. motif=pyridine nucleotide-disulphide oxidoreductases class-II active site. (336 aa)    
Predicted Functional Partners:
PH0178
226aa long hypothetical glutaredoxin-like protein; Similar to PIR:S54843 percent identity: 88.496 in 226aa.
 
 0.991
PH1217
216aa long hypothetical alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.941
PHS039
64aa long hypothetical protein; Similar to PIR:E64354 percent identity: 33.929 in 56aa.
     
 0.819
PH0710
460aa long hypothetical seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
  
 0.784
PH0056
230aa long hypothetical HESA protein; Similar to Swiss_Prot:P46048 percent identity: 44.037 in 223aa; Swiss_Prot:P18500 percent identity: 41.872 in 206aa; PIR:A49890 percent identity: 39.450 in 223aa.
  
  
 0.697
PH1130
170aa long hypothetical protein; Motif=prokaryotic membrane lipoprotein lipid attachment site.
  
 
 0.692
PH0184
149aa long hypothetical molybdopterinconverting factor, subunit; Similar to owl:MTCY16429 percent identity: 38.525 in 122aa; owl:ATAC00233312 percent identity: 34.752 in 141aa; Swiss_Prot:P30749 percent identity: 40.171 in 117aa. motif=tonB-dependent receptor proteins signatures.
  
  
 0.620
PH0314
896aa long hypothetical valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
   
 0.611
PH0121
1434aa long hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
      
 0.594
PH1478
629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
 
   
 0.560
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.