STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1593422aa long hypothetical glutamate dehydrogenase; Similar to owl:A47410 percent identity: 96.429 in 420aa; Swiss_Prot:P80319 percent identity: 95.952 in 420aa; owl:THCGLUDEHY percent identity: 87.799 in 419aa. motif=glu / Leu / Phe / Val dehydrogenases active site; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (422 aa)    
Predicted Functional Partners:
PH1282
314aa long hypothetical carbamate kinase (fucoxanthin chlorophyll a/c binding protein); Similar to owl:PFCPA percent identity: 89.103 in 312aa; owl:CPARCABDC3 percent identity: 51.780 in 311aa; owl:ECAE0003708 percent identity: 49.673 in 314aa.
     
 0.968
PH0876
472aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 76.972 in 476aa; owl:ECAE0003335 percent identity: 39.052 in 457aa; Swiss_Prot:P09832 percent identity: 37.251 in 466aa.
  
 0.957
PH1873
476aa long hypothetical glutamate synthase small chain; Similar to owl:D86223 percent identity: 82.553 in 472aa; PIR:JC5184 percent identity: 39.002 in 460aa; Swiss_Prot:P09832 percent identity: 36.947 in 472aa.
  
 0.957
PH0359
443aa long hypothetical glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.950
PH0771
391aa long hypothetical aspartate aminotransferase; Similar to PIR:A64300 percent identity: 48.098 in 386aa; PIR:JC4537 percent identity: 41.026 in 355aa; owl:TAX99521 percent identity: 40.390 in 363aa. motif=aminotransferases class-I pyridoxal-phosphate attachment site; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.927
PH1322
401aa long hypothetical aspartate aminotransferase; Similar to owl:HIU3271411 percent identity: 39.516 in 378aa; owl:MTCY2793 percent identity: 40.811 in 377aa; owl:D9086011 percent identity: 38.462 in 397aa.
  
 
 0.927
PH1955
227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]
    
  0.911
PH1041
389aa long hypothetical protein.
    
 0.905
PH1994
502aa long hypothetical glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
 0.869
PH1722
323aa long hypothetical 3-isopropylmalate dehydrogenase; May play a dual role in glutamate and lysine biosynthesis in vivo. Uses isocitrate and homoisocitrate at near equal efficiency and preferentially uses NAD over NADP.
  
 
 0.864
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.