node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PH0113 | PH0124 | gene:9377021 | gene:9377032 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 0.518 |
PH0113 | PH0195 | gene:9377021 | gene:9377105 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 0.940 |
PH0113 | PH0196 | gene:9377021 | gene:9377106 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 397aa long hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.935 |
PH0113 | PH1415 | gene:9377021 | gene:9378391 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 343aa long hypothetical 5' nuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.846 |
PH0113 | PH1564 | gene:9377021 | gene:9378554 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 564aa long hypothetical typeII DNA topoisomerase subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.806 |
PH0113 | PH1622 | gene:9377021 | gene:9378612 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 559aa long hypothetical DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.925 |
PH0113 | PH1650 | gene:9377021 | gene:9378643 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 220aa long hypothetical ribonuclease H II; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.879 |
PH0113 | PH1947 | gene:9377021 | gene:9378960 | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family. | 0.939 |
PH0124 | PH0113 | gene:9377032 | gene:9377021 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.518 |
PH0124 | PH0195 | gene:9377032 | gene:9377105 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 0.953 |
PH0124 | PH0196 | gene:9377032 | gene:9377106 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 397aa long hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.968 |
PH0124 | PH1415 | gene:9377032 | gene:9378391 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 343aa long hypothetical 5' nuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.741 |
PH0124 | PH1564 | gene:9377032 | gene:9378554 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 564aa long hypothetical typeII DNA topoisomerase subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.894 |
PH0124 | PH1622 | gene:9377032 | gene:9378612 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 559aa long hypothetical DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.535 |
PH0124 | PH1650 | gene:9377032 | gene:9378643 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 220aa long hypothetical ribonuclease H II; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.891 |
PH0124 | PH1947 | gene:9377032 | gene:9378960 | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family. | 0.952 |
PH0195 | PH0113 | gene:9377105 | gene:9377021 | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 468aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.940 |
PH0195 | PH0124 | gene:9377105 | gene:9377032 | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 437aa long hypothetical protein; Involved in regulation of DNA replication. | 0.953 |
PH0195 | PH0196 | gene:9377105 | gene:9377106 | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 397aa long hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.999 |
PH0195 | PH1415 | gene:9377105 | gene:9378391 | 346aa long hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synth [...] | 343aa long hypothetical 5' nuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.882 |