STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1830334aa long hypothetical glyceraldehyde-3-phosphate dehydrogenase; Similar to Swiss_Prot:P20286 percent identity: 90.719 in 334aa; Swiss_Prot:P10618 percent identity: 56.061 in 334aa; Swiss_Prot:P19315 percent identity: 57.751 in 335aa. motif=glyceraldehyde 3-phosphate dehydrogenase active site. (334 aa)    
Predicted Functional Partners:
PH1218
410aa long hypothetical phosphoglycerate kinase; Similar to Swiss_Prot:P50316 percent identity: 77.995 in 409aa; PIR:A64380 percent identity: 50.125 in 413aa; Swiss_Prot:P20971 percent identity: 44.275 in 401aa. motif=phosphoglycerate kinase signature.
 0.999
PH1884
231aa long hypothetical triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
PH1942
428aa long hypothetical phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.983
PH0759
390aa long hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
  
 
 0.981
PH0457
653aa long hypothetical protein; Similar to PIR:H64447 percent identity: 48.739 in 631aa. motif=crystallins beta and gamma 'Greek key' motif signature; eukaryotic thiol (cysteine) proteases active sites.
    
 0.977
PH0082
281aa long hypothetical protein; Similar to PIR:H64349 percent identity: 36.782 in 274aa; Belongs to the DeoC/FbaB aldolase family.
    
 0.962
PH1630
341aa long hypothetical protein.
  
 
 0.926
PH1009
191aa long hypothetical TATA-binding protein (transcription initiation factor TFIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
   
  
 0.868
PH1956
192aa long hypothetical protein.
    
 0.863
PH0359
443aa long hypothetical glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.855
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.