STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1897254aa long hypothetical protein; Similar to PIR:E64313 percent identity: 45.082 in 247aa. motif=inositol monophosphatase family signatures. (254 aa)    
Predicted Functional Partners:
PH1605
425aa long hypothetical protein.
  
 
 0.950
PH1074
277aa long hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates (GTP,UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus. NAD is the preferred substrate for the kinase, but NADH can also be used as phosphoryl acceptor.
 
  
 0.935
PH1579
173aa long hypothetical protein; Similar to PIR:D64443 percent identity: 53.623 in 143aa; owl:S75733 percent identity: 48.333 in 125aa.
 
  
 0.907
PH1219
423aa long hypothetical protein; motif=CDP-alcohol phosphatidyltransferases signature; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.903
PH1898
267aa long hypothetical protein; Similar to Swiss_Prot:P29085 percent identity: 83.117 in 77aa; PIR:H64354 percent identity: 32.824 in 267aa.
       0.819
PH1896
650aa long hypothetical ATP-dependent RNA helicase; Similar to PIR:H64487 percent identity: 42.424 in 695aa.
  
    0.780
PH0002
155aa long hypothetical transcription termination-antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
   
 
 0.773
PHS055
90aa long hypothetical DNA excision repair protein; Similar to PIR:H64487 percent identity:53.488 in 86aa; GENPEPT:U74491 percent identity:29.577 in 71aa; Swiss_Prot:P07903 percent identity:30.986 in 71aa.
  
    0.722
PH0466
514aa long hypothetical protein.
  
  
 0.718
PH1546
1117aa long hypothetical DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.683
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: medium (46%) [HD]