STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1916150aa long hypothetical leucine-responsive regulatory protein; Similar to owl:ATU39263 percent identity:34.028 in 144aa. (150 aa)    
Predicted Functional Partners:
PH1917
186aa long hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.710
PH1918
162aa long hypothetical protein.
       0.691
PH1915
396aa long hypothetical protein; Similar to PIR:C64506 percent identity: 51.187 in 396aa; PIR:G64505 percent identity: 45.288 in 395aa; owl:ECAE00019811 percent identity: 33.803 in 363aa.
       0.576
PH0045
155aa long hypothetical protein; Similar to owl:MTCY7130 percent identity:44.872 in 78aa.
  
     0.539
PH1919
307aa long hypothetical protein; Motif=short-chain dehydrogenases/reductases family signature.
       0.504
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (28%) [HD]