STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycbG-2YcbG; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (180 aa)    
Predicted Functional Partners:
mukE
MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
 
 
 0.917
mukB
MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
 
 
 0.912
mukF
MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
 
 
 0.891
yiiU
YiiU; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
   
 0.863
seqA
SeqA; Protein SeqA; Similar to Pantoea sp. At-9b, SeqA family protein (NCBI: ZP_05732386.1); COG: DNA replication, recombination and repair; Subcellular localization as predicted by Psort 2.0: Unknown.
  
   
 0.849
slmA
SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
      
 0.797
yhhL
YhhL; Inner Membrane Protein YhhL; Similar to Klebsiella pneumoniae subsp. pneumoniae MGH 78578, hypothetical protein KPN_03832 (NCBI: YP_001337486.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
  
     0.773
trpR
TrpR; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
  
     0.772
ycdY
YcdY; Dimethyl Sulfoxide Reductase Component Protein YcdY; Similar to Pantoea sp. At-9b, cytoplasmic chaperone TorD family protein (NCBI: ZP_05728462.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane.
  
     0.767
yoaH
YoaH; Hypothetical UPF0181 protein YoaH; Similar to Enterobacter sp. 638, hypothetical protein Ent638_2380 (NCBI: YP_001177100.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
  
     0.767
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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