STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyaRGyaR; Glyoxylate reductase; Similar to Pseudomonas putida KT2440, D-isomer specific 2-hydroxyacid dehydrogenase family protein (NCBI: NP_744678.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. (326 aa)    
Predicted Functional Partners:
serC
SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.964
serA
SerA; D-3-phosphoglycerate dehydrogenase; Similar to Klebsiella pneumoniae 342, D-isomer specific 2-hydroxyacid dehydrogenase family protein (NCBI: YP_002236948.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
  
 
0.924
gpmA
GpmA; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.908
gpmB-2
GpmB; Probable phosphoglycerate mutase GpmB; Similar to Pantoea sp. At-9b, Phosphoglycerate mutase (NCBI: ZP_05732509.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown.
    
  0.905
serA-2
SerA; D-3-phosphoglycerate dehydrogenase; Similar to Pantoea sp. At-9b, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (NCBI: ZP_05731464.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
  
 
0.905
PANA_1608
Hypothetical Protein; Similar to Pantoea sp. At-9b, conserved hypothetical protein (NCBI: ZP_05729489.1); COG: Unknown Function; Subcellular localization as predicted by Psort 2.0: Unknown.
       0.773
gnl-2
Gnl; Gluconolactonase precursor; Similar to Burkholderia phymatum STM815, SMP-30/gluconolaconase/LRE domain-containing protein (NCBI: YP_001862137.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
   
 0.600
thrA
ThrA; Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05729729.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.549
metL
MetL; Bifunctional aspartokinase/homoserine dehydrogenase II; Similar to Pantoea sp. At-9b, aspartate kinase (NCBI: ZP_05730334.1); COG: Amino acid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.549
yeaU
YeaU; Probable tartrate dehydrogenase/decarboxylase; Similar to Pantoea sp. At-9b, tartrate dehydrogenase (NCBI: ZP_05732303.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
  
 0.446
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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