STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycdW-2YcdW; Putative 2-hydroxyacid dehydrogenase YcdW; Similar to Pantoea sp. At-9b, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (NCBI: ZP_05732610.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. (308 aa)    
Predicted Functional Partners:
aceA
AceA; Isocitrate lyase; Similar to Pantoea sp. At-9b, isocitrate lyase (NCBI: ZP_05731760.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
   
 
 0.937
aceB
AceB; Malate synthase A; Similar to Pantoea sp. At-9b, malate synthase A (NCBI: ZP_05731759.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
     
 0.936
tkrA
TkrA; 2-ketogluconate reductase; Similar to Pantoea sp. At-9b, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (NCBI: ZP_05729655.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
 
  
 
0.915
ycdW
YcdW; Putative 2-hydroxyacid dehydrogenase YcdW; Similar to Pantoea sp. At-9b, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (NCBI: ZP_05728460.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
  
 
0.915
gph
Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.910
aldA-4
AldA; Aldehyde dehydrogenase A; Similar to Neisseria gonorrhoeae SK-93-1035, LOW QUALITY PROTEIN: aldehyde dehydrogenase A (NCBI: ZP_06152557.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
  
 0.909
eda
Eda; KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase]; Similar to Pantoea sp. At-9b, 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI: ZP_05728662.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic.
    
  0.904
garK
GarK; Glycerate kinase 2; Similar to Pantoea sp. At-9b, glycerate kinase (NCBI: ZP_05732156.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the glycerate kinase type-1 family.
    
  0.901
garR
GarR; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
    
  0.901
gloA
GloA; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
 0.900
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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