node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hpaC | ycdC-3 | PANA_3281 | PANA_4032 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.644 |
hpaC | ycdH | PANA_3281 | PANA_4038 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdH; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.912 |
hpaC | ycdI-2 | PANA_3281 | PANA_4037 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdI; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted. | 0.504 |
hpaC | ycdJ-2 | PANA_3281 | PANA_4036 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdJ; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.533 |
hpaC | ycdL-2 | PANA_3281 | PANA_4034 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdL; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily. | 0.935 |
hpaC | ycdM | PANA_3281 | PANA_4033 | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdM; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.948 |
ycdC-3 | hpaC | PANA_4032 | PANA_3281 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.644 |
ycdC-3 | ycdH | PANA_4032 | PANA_4038 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdH; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.454 |
ycdC-3 | ycdJ-2 | PANA_4032 | PANA_4036 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdJ; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.647 |
ycdC-3 | ycdK | PANA_4032 | PANA_4035 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdK; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | 0.482 |
ycdC-3 | ycdL-2 | PANA_4032 | PANA_4034 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdL; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily. | 0.553 |
ycdC-3 | ycdM | PANA_4032 | PANA_4033 | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | YcdM; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.592 |
ycdG | ycdH | PANA_4039 | PANA_4038 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdH; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.716 |
ycdG | ycdI-2 | PANA_4039 | PANA_4037 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdI; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted. | 0.721 |
ycdG | ycdJ-2 | PANA_4039 | PANA_4036 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdJ; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.678 |
ycdG | ycdK | PANA_4039 | PANA_4035 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdK; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | 0.597 |
ycdG | ycdL-2 | PANA_4039 | PANA_4034 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdL; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily. | 0.541 |
ycdG | ycdM | PANA_4039 | PANA_4033 | YcdG; Putative purine permease YcdG; Similar to Serratia proteamaculans 568, uracil-xanthine permease (NCBI: YP_001478049.1); COG: Nucleotide transport and metabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. | YcdM; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.578 |
ycdH | hpaC | PANA_4038 | PANA_3281 | YcdH; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | HpaC; 4-hydroxyphenylacetate 3-monooxygenase-reductase component; Similar to Bordetella avium 197N, 4-hydroxyphenylacetate 3-monooxygenase,reductase component (NCBI: YP_785494.1); COG: Energy production and conversion; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.912 |
ycdH | ycdC-3 | PANA_4038 | PANA_4032 | YcdH; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | YcdC; Putative HTH-type transcriptional regulator YcdC; Similar to Serratia proteamaculans 568, TetR family transcriptional regulator (NCBI: YP_001478055.1); COG: Transcription; Subcellular localization as predicted by Psort 2.0: Unknown. | 0.454 |