STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHO66392.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (209 aa)    
Predicted Functional Partners:
KHO65494.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.897
KHO64721.1
Phenylacetic acid degradation protein PaaY; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.897
KHO63776.1
Anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.897
KHO65809.1
Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.879
KHO66064.1
Transporter; Role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.710
KHO63783.1
Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
 
0.699
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
    0.573
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.573
KHO65438.1
Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.571
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.513
Your Current Organism:
Pseudomonas flexibilis
NCBI taxonomy Id: 706570
Other names: ATCC 29606, JCM 14085 [[Pseudomonas tuomuerensis]], LMG 29034, LMG:29034, P. flexibilis, Pseudomonas tuomuerensis, Pseudomonas tuomuerensis Xin et al. 2009, Serpens flexibilis, strain 78-123 [[Pseudomonas tuomuerensis]]
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