STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6WVA0_TRICAChloride channel protein. (782 aa)    
Predicted Functional Partners:
D6WMS9_TRICA
Osteopetrosis-associated transmembrane protein 1-like Protein.
    
 0.986
A0A139WI57
Anion exchange protein.
   
  
 0.635
A0A139WM41
Anion exchange protein.
   
  
 0.635
D6X224_TRICA
Inositol polyphosphate 5-phosphatase OCRL-1-like Protein.
   
  
 0.618
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.617
D6WBT3_TRICA
U4/U6 small nuclear ribonucleoprotein Prp3-like Protein.
      
 0.581
A0A139W8N6
Sodium/hydrogen exchanger 8-like Protein.
  
  
 0.562
G6pd
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
  
  
 0.551
D6WHX2_TRICA
Methylosome subunit pICln-like Protein.
      
 0.545
D6WRY4_TRICA
G protein alpha s subunit-like Protein.
      
 0.516
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.