STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HemHem. (1122 aa)    
Predicted Functional Partners:
D6W6N5_TRICA
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.998
A0A139WFU2
Uncharacterized protein.
    
 0.995
D6WUN3_TRICA
Wiskott-Aldrich syndrome protein family member 3-like Protein.
    
 0.995
D6WAE9_TRICA
Abl interactor 2-like Protein.
    
 0.990
A0A139WN19
Uncharacterized protein.
    
 0.946
D6W9X2_TRICA
Uncharacterized protein.
    
 0.889
D6WDF4_TRICA
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.853
A0A139WDC8
Actin-related protein 2/3 complex subunit 2-like Protein.
     
 0.828
A0A139WAU9
Transmembrane protein 161B-like Protein.
 
      0.792
D6WGX8_TRICA
Actin-related protein 3-like Protein; Belongs to the actin family.
    
 0.792
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.