STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fezFez family zinc finger protein 2-like Protein (344 aa)    
Predicted Functional Partners:
Six3
Optix protein; Sine oculis-related homeobox 3
   
 
 0.815
otp
Homeobox protein orthopedia-like Protein; Orthopedia
   
 
 0.800
Otd-2
Orthodenticle-2; Orthodenticle-2 protein
   
 
 0.718
LOC655440
Kelch-like protein diablo
   
 
 0.715
Wnt8/D
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors
   
 
 0.677
nkx2.1
Scarecrow
   
 
 0.672
Wg
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors
   
 
 0.660
TC011785-PA
Fringe glycosyltransferase-like Protein
      
 0.657
LOC656415
Shaven
    
 
 0.633
LOC659897
Protein elav-like protein
   
  
 0.575
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, Tribolium castaneum, red flour beetle, rust-red flour beetle
Server load: low (7%) [HD]