node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atpE_1 | ntpB | BW727_100537 | BW727_100541 | V-type proton ATPase subunit E. | V-type sodium ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. | 0.999 |
atpE_1 | ntpC | BW727_100537 | BW727_100538 | V-type proton ATPase subunit E. | V-type sodium ATPase subunit C. | 0.999 |
atpE_1 | spsB | BW727_100537 | BW727_100702 | V-type proton ATPase subunit E. | Signal peptidase IB; Belongs to the peptidase S26 family. | 0.753 |
ctpA | deoD | BW727_100700 | BW727_100699 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | Purine nucleoside phosphorylase DeoD-type. | 0.721 |
ctpA | rbgA | BW727_100700 | BW727_100703 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.595 |
ctpA | rnhB | BW727_100700 | BW727_100704 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.604 |
ctpA | sipV | BW727_100700 | BW727_100701 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | Signal peptidase I V; Belongs to the peptidase S26 family. | 0.827 |
ctpA | spsB | BW727_100700 | BW727_100702 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | Signal peptidase IB; Belongs to the peptidase S26 family. | 0.817 |
ctpA | topA | BW727_100700 | BW727_100706 | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.469 |
deoD | ctpA | BW727_100699 | BW727_100700 | Purine nucleoside phosphorylase DeoD-type. | Carboxy-terminal processing protease CtpA; Belongs to the peptidase S41A family. | 0.721 |
deoD | rbgA | BW727_100699 | BW727_100703 | Purine nucleoside phosphorylase DeoD-type. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.505 |
deoD | rnhB | BW727_100699 | BW727_100704 | Purine nucleoside phosphorylase DeoD-type. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.506 |
deoD | sipV | BW727_100699 | BW727_100701 | Purine nucleoside phosphorylase DeoD-type. | Signal peptidase I V; Belongs to the peptidase S26 family. | 0.636 |
deoD | spsB | BW727_100699 | BW727_100702 | Purine nucleoside phosphorylase DeoD-type. | Signal peptidase IB; Belongs to the peptidase S26 family. | 0.644 |
deoD | topA | BW727_100699 | BW727_100706 | Purine nucleoside phosphorylase DeoD-type. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.410 |
lepA | spsB | BW727_100691 | BW727_100702 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase IB; Belongs to the peptidase S26 family. | 0.754 |
lepA | topA | BW727_100691 | BW727_100706 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.503 |
ntpB | atpE_1 | BW727_100541 | BW727_100537 | V-type sodium ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. | V-type proton ATPase subunit E. | 0.999 |
ntpB | ntpC | BW727_100541 | BW727_100538 | V-type sodium ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. | V-type sodium ATPase subunit C. | 0.999 |
ntpB | spsB | BW727_100541 | BW727_100702 | V-type sodium ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. | Signal peptidase IB; Belongs to the peptidase S26 family. | 0.641 |