STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV66914.1COGs: COG2225 Malate synthase; InterPro IPR006252: IPR001465; KEGG: ddr:Deide_11990 malate synthase; PFAM: Malate synthase; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: Malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A. (523 aa)    
Predicted Functional Partners:
ADV66913.1
COGs: COG2224 Isocitrate lyase; InterPro IPR006254: IPR000918; KEGG: dge:Dgeo_1287 isocitrate lyase; PFAM: Isocitrate lyase/phosphorylmutase; PRIAM: Isocitrate lyase; SPTR: Isocitrate lyase; TIGRFAM: Isocitrate lyase; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase.
 
 0.999
ADV67761.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.975
ADV67946.1
2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR011278; KEGG: dra:DR_0757 citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
   
 0.964
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.952
ADV65958.1
Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
   
 0.952
ADV67682.1
Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_2396 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
   
 0.952
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.929
ADV66196.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155; KEGG: bts:Btus_3242 acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.925
ADV66835.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155; KEGG: ddr:Deide_01560 putative acetyl-CoA acetyltransferase, (acetoacetyl-CoA thiolase); PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Putative Acetyl-CoA acetyltransferase, (Acetoacetyl-CoA thiolase); TIGRFAM: Thiolase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.925
ADV67098.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155: IPR020616: IPR020617; KEGG: ddr:Deide_16670 putative acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Putative acetyl-CoA C-acetyltransferase (Acetoacetyl-CoA thiolase); TIGRFAM: Thiolase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.925
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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