STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV73504.1Methionine synthase II (cobalamin-independent); PFAM: Cobalamin-independent synthase, Catalytic domain. (368 aa)    
Predicted Functional Partners:
AEV73506.1
PFAM: Methane/Phenol/Toluene Hydroxylase.
    
  0.931
AEV73507.1
PFAM: MmoB/DmpM family; manually curated.
    
  0.930
AEV73509.1
Flavodoxin reductase family protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
    
 0.928
AEV73508.1
PFAM: Methane/Phenol/Toluene Hydroxylase.
    
  0.924
AEV75603.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.871
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.864
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.786
AEV72297.1
Hypothetical protein.
  
 
 0.767
AEV71157.1
OAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
  
 
 0.715
AEV73505.1
Hypothetical protein.
       0.651
Your Current Organism:
Mycolicibacterium rhodesiae NBB3
NCBI taxonomy Id: 710685
Other names: M. rhodesiae NBB3, Mycobacterium rhodesiae NBB3
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