node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEV71524.1 | AEV72431.1 | MycrhN_0894 | MycrhN_1820 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.914 |
AEV71524.1 | AEV73813.1 | MycrhN_0894 | MycrhN_3288 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | DNA ligase D/DNA polymerase LigD; PFAM: ATP dependent DNA ligase domain; Eukaryotic and archaeal DNA primase small subunit; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain; DNA ligase D; DNA ligase D, 3'-phosphoesterase domain; DNA polymerase LigD, polymerase domain. | 0.662 |
AEV71524.1 | AEV74276.1 | MycrhN_0894 | MycrhN_3758 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | DNA repair exonuclease; PFAM: Calcineurin-like phosphoesterase. | 0.565 |
AEV71524.1 | AEV75570.1 | MycrhN_0894 | MycrhN_5092 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain. | 0.812 |
AEV71524.1 | dinB-3 | MycrhN_0894 | MycrhN_6006 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.657 |
AEV71524.1 | polA | MycrhN_0894 | MycrhN_4608 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.932 |
AEV71524.1 | recA | MycrhN_0894 | MycrhN_5602 | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.826 |
AEV71866.1 | AEV72431.1 | MycrhN_1243 | MycrhN_1820 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.887 |
AEV71866.1 | AEV73813.1 | MycrhN_1243 | MycrhN_3288 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA ligase D/DNA polymerase LigD; PFAM: ATP dependent DNA ligase domain; Eukaryotic and archaeal DNA primase small subunit; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain; DNA ligase D; DNA ligase D, 3'-phosphoesterase domain; DNA polymerase LigD, polymerase domain. | 0.685 |
AEV71866.1 | AEV74276.1 | MycrhN_1243 | MycrhN_3758 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA repair exonuclease; PFAM: Calcineurin-like phosphoesterase. | 0.433 |
AEV71866.1 | AEV75570.1 | MycrhN_1243 | MycrhN_5092 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain. | 0.810 |
AEV71866.1 | polA | MycrhN_1243 | MycrhN_4608 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.907 |
AEV71866.1 | recA | MycrhN_1243 | MycrhN_5602 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.569 |
AEV72431.1 | AEV71524.1 | MycrhN_1820 | MycrhN_0894 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | 0.914 |
AEV72431.1 | AEV71866.1 | MycrhN_1820 | MycrhN_1243 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.887 |
AEV72431.1 | AEV73813.1 | MycrhN_1820 | MycrhN_3288 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase D/DNA polymerase LigD; PFAM: ATP dependent DNA ligase domain; Eukaryotic and archaeal DNA primase small subunit; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain; DNA ligase D; DNA ligase D, 3'-phosphoesterase domain; DNA polymerase LigD, polymerase domain. | 0.891 |
AEV72431.1 | AEV74276.1 | MycrhN_1820 | MycrhN_3758 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair exonuclease; PFAM: Calcineurin-like phosphoesterase. | 0.625 |
AEV72431.1 | AEV75570.1 | MycrhN_1820 | MycrhN_5092 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain. | 0.948 |
AEV72431.1 | dinB-3 | MycrhN_1820 | MycrhN_6006 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.861 |
AEV72431.1 | ligA | MycrhN_1820 | MycrhN_5940 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.429 |