STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU49116.11D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-gluc opyranosidedeacetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR017810: IPR003737; KEGG: sma:SAV_3138 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; PFAM: LmbE family protein; SPTR: Putative N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D -glucopyranosidedeacetylase; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Belongs to [...] (279 aa)    
Predicted Functional Partners:
mshA
UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
  
 0.878
mshC
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
 
 0.758
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
    0.750
ADU49118.1
GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225: IPR006298: IPR000795: IPR004161: IPR 000640; KEGG: sro:Sros_7974 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Small GTP-binding protein domain:GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein T [...]
       0.739
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.703
ADU49117.1
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: nca:Noca_2400 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Putative ABC transporter solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
       0.686
ADU48265.1
KEGG: sen:SACE_2204 phosphatidylinositol 3-and 4-kinase, catalytic; SPTR: Phosphatidylinositol 3-and 4-kinase, catalytic; PFAM: Phosphatidylinositol 3- and 4-kinase; TIGRFAM: conserved hypothetical protein.
  
     0.671
ADU48264.1
KEGG: kra:Krad_1834 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3090); TIGRFAM: conserved hypothetical protein.
  
     0.670
ADU49538.1
LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: mtu:Rv0323c hypothetical protein; PFAM: LmbE family protein; SPTR: Putative uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase.
  
     0.667
ADU49119.1
NUDIX hydrolase; InterPro IPR020476: IPR000086: IPR020084; KEGG: xce:Xcel_0048 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: Putative mutT-like protein; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein.
       0.662
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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