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cysK protein (Haemophilus influenzae) - STRING interaction network
"cysK" - Cysteine synthetase in Haemophilus influenzae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthetase (316 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase (267 aa)
 
  0.999
metC
Cystathionine beta-lyase (396 aa)
  0.966
metB
Cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia (By similarity) (381 aa)
  0.964
thrA
Aspartate kinase (EC-1.1.1.3 2.7.2.4) (815 aa)
   
 
  0.942
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (167 aa)
       
  0.919
cysS
cysteinyl-tRNA synthetase (459 aa)
 
  0.916
cysZ
Sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway (272 aa)
   
   
  0.877
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (756 aa)
     
 
  0.846
guaB
Inosine 5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (488 aa)
       
  0.823
coaBC
Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4’-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4’-phosphopantotheine (By similarity) (400 aa)
   
 
  0.813
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: Bacterium influenzae, Coccobacillus pfeifferi, H. influenzae, H. influenzae Rd KW20, Haemophilus influenzae, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20, Haemophilus meningitidis, Influenza-bacillus, Mycobacterium influenzae
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