STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eda4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase (eda); Similar to GB:L20897 GB:M87458 GB:X63694 GB:X68871 PID:145827 percent identity: 37.31; identified by sequence similarity; putative; Belongs to the KHG/KDPG aldolase family. (212 aa)    
Predicted Functional Partners:
kdgK
2-dehydro-3-deoxygluconokinase (kdgK); Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
 
 
 0.987
HI_0048
Oxidoreductase; Similar to GB:AL009126 percent identity: 48.39; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.936
HI_1163
Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative.
   
 
 0.793
ilvD
Dihydroxyacid dehydratase (ilvD); Similar to SP:P05791 GB:M10313 GB:K03503 GB:M32253 GB:X02413 percent identity: 76.87; identified by sequence similarity; putative; Belongs to the IlvD/Edd family.
  
 
 0.742
HI_0143
Conserved hypothetical protein; Similar to GB:M81878 SP:P26833 PID:144859 percent identity: 34.08; identified by sequence similarity; putative.
 
  
 0.740
zwf
Glucose-6-phosphate 1-dehydrogenase (zwf); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
  
 0.724
pgi
Glucose-6-phosphate isomerase (pgi); Similar to SP:P11537 GB:X15196 PID:396360 PID:42377 GB:U00096 percent identity: 77.05; identified by sequence similarity; putative.
  
 
 0.722
pykA
Pyruvate kinase, type II (pykA); Similar to GB:M63703 SP:P21599 GB:M87660 PID:147459 PID:146878 percent identity: 77.24; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
    
 0.719
gapA
Glyceraldehyde-3-phosphate dehydrogenase (gapdH); Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
  
 
 0.709
tal
Transaldolase B (talB); Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.705
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.