node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_0090 | HI_0175 | HI_0090 | HI_0175 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity. | 0.698 |
HI_0090 | HI_1036 | HI_0090 | HI_1036 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Similar to PID:801880 SP:P52059 PID:801882 percent identity: 41.24; identified by sequence similarity; putative. | 0.570 |
HI_0090 | HI_1208 | HI_0090 | HI_1208 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. | 0.424 |
HI_0090 | metXA | HI_0090 | HI_1263 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Homoserine acetyltransferase (met2); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl- enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine. | 0.444 |
HI_0090 | mtnN | HI_0090 | HI_1216 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.623 |
HI_0090 | murF | HI_0090 | HI_1134 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | UDP-MurNAc-pentapeptide synthetase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.443 |
HI_0090 | pdxY | HI_0090 | HI_0405 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyridoxine kinase, putative; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.508 |
HI_0090 | rpmC | HI_0090 | HI_0785 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Ribosomal protein L29 (rpL29); Similar to SP:P55840 PID:1841330 percent identity: 90.48; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family. | 0.412 |
HI_0090 | thrA | HI_0090 | HI_0089 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.456 |
HI_0090 | tpiA | HI_0090 | HI_0678 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.405 |
HI_0175 | HI_0090 | HI_0175 | HI_0090 | Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.698 |
HI_1036 | HI_0090 | HI_1036 | HI_0090 | Conserved hypothetical protein; Similar to PID:801880 SP:P52059 PID:801882 percent identity: 41.24; identified by sequence similarity; putative. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.570 |
HI_1208 | HI_0090 | HI_1208 | HI_0090 | Conserved hypothetical protein; Similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.424 |
metXA | HI_0090 | HI_1263 | HI_0090 | Homoserine acetyltransferase (met2); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl- enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.444 |
metXA | thrA | HI_1263 | HI_0089 | Homoserine acetyltransferase (met2); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl- enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine. | Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.983 |
mtnN | HI_0090 | HI_1216 | HI_0090 | Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.623 |
murF | HI_0090 | HI_1134 | HI_0090 | UDP-MurNAc-pentapeptide synthetase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.443 |
pdxY | HI_0090 | HI_0405 | HI_0090 | Pyridoxine kinase, putative; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.508 |
rpmC | HI_0090 | HI_0785 | HI_0090 | Ribosomal protein L29 (rpL29); Similar to SP:P55840 PID:1841330 percent identity: 90.48; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.412 |
thrA | HI_0090 | HI_0089 | HI_0090 | Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.456 |