node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_0175 | rluD | HI_0175 | HI_0176 | Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity. | sfhB protein (sfhB); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.805 |
HI_1151 | obg | HI_1151 | HI_0877 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.611 |
HI_1151 | rluD | HI_1151 | HI_0176 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | sfhB protein (sfhB); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.688 |
HI_1151 | rplM | HI_1151 | HI_1443 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.611 |
HI_1151 | rplQ | HI_1151 | HI_0803 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | Ribosomal protein L17 (rplQ); Similar to GB:J01685 SP:P02416 GB:X00766 PID:147716 PID:42800 percent identity: 89.76; identified by sequence similarity; putative. | 0.611 |
HI_1151 | rplT | HI_1151 | HI_1320 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.611 |
HI_1151 | rplU | HI_1151 | HI_0880 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.615 |
HI_1151 | rsfS | HI_1151 | HI_0034 | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.612 |
mnmE | obg | HI_1002 | HI_0877 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.499 |
mnmE | rluD | HI_1002 | HI_0176 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | sfhB protein (sfhB); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.720 |
mnmE | rplM | HI_1002 | HI_1443 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.738 |
mnmE | rplQ | HI_1002 | HI_0803 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L17 (rplQ); Similar to GB:J01685 SP:P02416 GB:X00766 PID:147716 PID:42800 percent identity: 89.76; identified by sequence similarity; putative. | 0.823 |
mnmE | rplU | HI_1002 | HI_0880 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.811 |
mnmE | rsfS | HI_1002 | HI_0034 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.795 |
mnmE | truD | HI_1002 | HI_0701 | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.796 |
obg | HI_1151 | HI_0877 | HI_1151 | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family. | 0.611 |
obg | mnmE | HI_0877 | HI_1002 | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.499 |
obg | rluD | HI_0877 | HI_0176 | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | sfhB protein (sfhB); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.780 |
obg | rplM | HI_0877 | HI_1443 | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.719 |
obg | rplQ | HI_0877 | HI_0803 | GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L17 (rplQ); Similar to GB:J01685 SP:P02416 GB:X00766 PID:147716 PID:42800 percent identity: 89.76; identified by sequence similarity; putative. | 0.785 |