node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_1163 | gdhA | HI_1163 | HI_0189 | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.717 |
HI_1163 | glnA | HI_1163 | HI_0865 | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | Glutamine synthetase (glnA); Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.531 |
HI_1163 | mdh | HI_1163 | HI_1210 | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.800 |
HI_1163 | napF | HI_1163 | HI_0342 | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | Ferredoxin-type protein (napF); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | 0.873 |
HI_1163 | sucC | HI_1163 | HI_1196 | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | succinyl-CoA synthetase, beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.401 |
aspC | gdhA | HI_1617 | HI_0189 | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.853 |
aspC | mdh | HI_1617 | HI_1210 | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.766 |
aspC | pheA | HI_1617 | HI_1145 | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.925 |
aspC | sucC | HI_1617 | HI_1196 | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | succinyl-CoA synthetase, beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.608 |
aspC | tyrA | HI_1617 | HI_1290 | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Chorismate mutase / prephenate dehydrogenase (tyrA); Similar to SP:Q02287 GB:M74135 GB:X60420 PID:415010 PID:43345 percent identity: 58.86; identified by sequence similarity; putative. | 0.921 |
gdhA | HI_1163 | HI_0189 | HI_1163 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. | 0.717 |
gdhA | aspC | HI_0189 | HI_1617 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.853 |
gdhA | glnA | HI_0189 | HI_0865 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Glutamine synthetase (glnA); Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.782 |
gdhA | glyA | HI_0189 | HI_0889 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Serine hydroxymethyltransferase (serine methylase) (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.709 |
gdhA | mdh | HI_0189 | HI_1210 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.738 |
gdhA | napF | HI_0189 | HI_0342 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Ferredoxin-type protein (napF); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | 0.706 |
gdhA | pheA | HI_0189 | HI_1145 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.736 |
gdhA | purL | HI_0189 | HI_0752 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Phosphoribosylformylglycinamidine synthase (purL); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.744 |
gdhA | sucC | HI_0189 | HI_1196 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | succinyl-CoA synthetase, beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.748 |
gdhA | tyrA | HI_0189 | HI_1290 | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | Chorismate mutase / prephenate dehydrogenase (tyrA); Similar to SP:Q02287 GB:M74135 GB:X60420 PID:415010 PID:43345 percent identity: 58.86; identified by sequence similarity; putative. | 0.821 |