Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiB | cpdA | HI_0066 | HI_0399 | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | 0.722 |
| amiB | guaA | HI_0066 | HI_0222 | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | 0.883 |
| amiB | mazG | HI_0066 | HI_0460 | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | 0.617 |
| amiB | pyrR | HI_0066 | HI_0459 | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Pyrimidine operon regulatory protein (pyrR); Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.577 |
| cpdA | amiB | HI_0399 | HI_0066 | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.722 |
| cpdA | guaA | HI_0399 | HI_0222 | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | 0.727 |
| cpdA | mazG | HI_0399 | HI_0460 | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | 0.633 |
| dcd | mazG | HI_0133 | HI_0460 | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | 0.792 |
| dcd | ndk | HI_0133 | HI_0876 | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.623 |
| dcd | nrdD | HI_0133 | HI_0075 | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | Anaerobic ribonucleoside-triphosphate reductase (nrdD); Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anaerobic ribonucleoside-triphosphate reductase family. | 0.771 |
| glpK | mazG | HI_0691 | HI_0460 | Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | 0.651 |
| guaA | amiB | HI_0222 | HI_0066 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.883 |
| guaA | cpdA | HI_0222 | HI_0399 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | 0.727 |
| guaA | mazG | HI_0222 | HI_0460 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | 0.701 |
| guaA | ndk | HI_0222 | HI_0876 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.485 |
| guaA | pyrR | HI_0222 | HI_0459 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Pyrimidine operon regulatory protein (pyrR); Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.400 |
| guaA | relA | HI_0222 | HI_0334 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | GTP pyrophosphokinase (relA); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.423 |
| mazG | amiB | HI_0460 | HI_0066 | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.617 |
| mazG | cpdA | HI_0460 | HI_0399 | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May coordinate responses to nutritional stress, ensuring optimal competence development. Belongs to the cAMP phosphodiesterase class-III family. | 0.633 |
| mazG | dcd | HI_0460 | HI_0133 | mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...] | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | 0.792 |
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