STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpRGlycerol-3-phosphate regulon repressor (glpR); Repressor of the glycerol-3-phosphate regulon. (255 aa)    
Predicted Functional Partners:
glpG
Glp protein, putative; Rhomboid-type serine protease that catalyzes intramembrane proteolysis; Belongs to the peptidase S54 family.
     
 0.723
fruK
1-phosphofructokinase (fruK); Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096 percent identity: 55.41; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.690
rluA
Conserved hypothetical protein; Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.
     
 0.683
fruA
PTS system, fructose-specific IIBC component (fruA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
 
  
 0.664
rapA
ATP-dependent helicase (hepA); Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
       0.600
fucR
L-fucose operon activator (fucR); Transcriptional activator of the fuc operon.
 
   
0.579
fucA
L-fuculose phosphate aldolase (fucA); Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
  
  
 0.419
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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