STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igaImmunoglobin A1 protease (iga1); Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments. (1694 aa)    
Predicted Functional Partners:
HI_1054
Conserved hypothetical protein; Similar to PID:1381738 percent identity: 92.49; identified by sequence similarity; putative.
  
     0.747
HI_1058
Predicted coding region HI1058; Hypothetical protein; identified by GeneMark; putative.
  
     0.745
HI_1055
Predicted coding region HI1055; Hypothetical protein; identified by GeneMark; putative.
  
     0.736
amiB
N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
  
 0.727
tbpA
Transferrin-binding protein 1 precursor (tbp1); Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family.
 
     0.723
licB
Lic-1 operon protein (licB); Similar to GB:M27280 SP:P14182 percent identity: 99.01; identified by sequence similarity; putative.
  
     0.723
ftsA
Cell division protein (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
   
 
 0.694
HI_1410
Predicted coding region HI1410; Hypothetical protein; identified by GeneMark; putative.
 
    0.664
HI_0552
Predicted coding region HI0552; Hypothetical protein; identified by GeneMark; putative.
  
     0.637
HI_0712
Hemoglobin-binding protein; Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
  
   
 0.636
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.