STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgbEL-ribulose-5-phosphate 4-epimerase (araD); Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). May be involved in the utilization of 2,3-diketo-L-gulonate. (231 aa)    
Predicted Functional Partners:
sgbU
Hexulose-6-phosphate isomerase, putative; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate.
  
 0.997
sgbH
Hexulose-6-phosphate synthase, putative; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P; Belongs to the HPS/KGPDC family. KGPDC subfamily.
 
 
 0.944
lyx
L-xylulose kinase (lyx); Similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 percent identity: 53.93; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
 
 
  0.873
citE
Citrate lyase, beta chain (citE); Represents a citryl-ACP lyase; Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
   
    0.588
HI_1028
Conserved hypothetical protein; Similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 percent identity: 55.80; identified by sequence similarity; putative.
       0.583
rpe
Ribulose-phosphate 3-epimerase (dod); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.574
HI_1029
Conserved hypothetical transmembrane protein; Similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 percent identity: 65.88; identified by sequence similarity; putative.
       0.516
HI_1030
Conserved hypothetical transmembrane protein; Similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 percent identity: 37.50; identified by sequence similarity; putative.
       0.516
xylB
Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
 
 
  0.502
qseB
Transcriptional regulatory protein (ygiX); Member of a two-component regulatory system QseB/QseC.
      
 0.479
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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