STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HI_1032Transcriptional regulator, putative; Similar to SP:P37671 PID:466712 GB:U00096 PID:1789999 percent identity: 63.74; identified by sequence similarity; putative. (268 aa)    
Predicted Functional Partners:
pxpB
Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.710
sgbH
Hexulose-6-phosphate synthase, putative; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P; Belongs to the HPS/KGPDC family. KGPDC subfamily.
     
 0.703
atoB
acetyl-CoA acetyltransferase (atoB); Similar to GB:U00096 SP:P76461 PID:1736879 PID:1788554 PID:1799573 percent identity: 66.92; identified by sequence similarity; putative.
  
 
 0.672
pxpC
Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.662
ltnD
3-hydroxyisobutyrate dehydrogenase, putative; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
  
  
  0.653
dlgD
Conserved hypothetical protein; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
 
     0.653
lldD
L-lactate dehydrogenase (lctD); Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
 
 
  0.616
ackA
Acetate kinase (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.598
HI_1029
Conserved hypothetical transmembrane protein; Similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 percent identity: 65.88; identified by sequence similarity; putative.
 
  
  0.591
leuA
2-isopropylmalate synthase (leuA); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
  0.573
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.