node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr | ddl | HI_1575 | HI_1140 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | 0.874 |
alr | mraY | HI_1575 | HI_1135 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase E (mraY); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.533 |
alr | murB | HI_1575 | HI_0268 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylenolpyruvoylglucosamine reductase (murB); Cell wall formation. | 0.733 |
alr | murC | HI_1575 | HI_1139 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family. | 0.694 |
alr | murD | HI_1575 | HI_1136 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.727 |
alr | murE | HI_1575 | HI_1133 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramyl-tripeptide synthetase (murE); Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.773 |
alr | murF | HI_1575 | HI_1134 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-MurNAc-pentapeptide synthetase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.985 |
alr | murG | HI_1575 | HI_1138 | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.463 |
ddl | alr | HI_1140 | HI_1575 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.874 |
ddl | ftsI | HI_1140 | HI_1132 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | Penicillin-binding protein 3 (ftsI); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.806 |
ddl | ftsW | HI_1140 | HI_1137 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | Cell division protein (ftsW); Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.876 |
ddl | mraY | HI_1140 | HI_1135 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase E (mraY); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.904 |
ddl | murB | HI_1140 | HI_0268 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase (murB); Cell wall formation. | 0.888 |
ddl | murC | HI_1140 | HI_1139 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | UDP-N-acetylmuramate--alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ddl | murD | HI_1140 | HI_1136 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.973 |
ddl | murE | HI_1140 | HI_1133 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | UDP-N-acetylmuramyl-tripeptide synthetase (murE); Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.941 |
ddl | murF | HI_1140 | HI_1134 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | UDP-MurNAc-pentapeptide synthetase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.990 |
ddl | murG | HI_1140 | HI_1138 | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.957 |
ftsI | ddl | HI_1132 | HI_1140 | Penicillin-binding protein 3 (ftsI); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | D-alanine--D-alanine ligase (ddlB); Cell wall formation. | 0.806 |
ftsI | ftsW | HI_1132 | HI_1137 | Penicillin-binding protein 3 (ftsI); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein (ftsW); Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.985 |