STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pntANAD(P) transhydrogenase, subunit alpha (pntA); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (512 aa)    
Predicted Functional Partners:
pntB
NAD(P) transhydrogenase, subunit beta (pntB); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.825
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.600
maeB
Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
     
 0.474
rpoC
DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.461
pheT
phenylalanyl-tRNA synthetase, beta subunit (pheT); Similar to GB:K02844 SP:P07395 PID:146346 PID:43071 GB:U00096 percent identity: 65.28; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
   
  
 0.432
glgP
Glycogen phosphorylase (glgP); Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity).
       0.418
aspC
Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
 
 
    0.417
PGdx
Membrane protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; In the C-terminal section; belongs to the glutaredoxin family.
      
 0.400
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.