STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HI_1453Uncharacterized protein HI_1453; Similar to GB:AL009126 percent identity: 30.84; identified by sequence similarity; putative; Belongs to the thioredoxin family (156 aa)    
Predicted Functional Partners:
msrAB
Peptide methionine sulfoxide reductase MsrA/MsrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
 
 0.995
HI_1454
Putative cytochrome c-type biogenesis protein HI_1454; Could be involved in cytochrome c synthesis
   
 0.990
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
   
 
  0.901
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Similar to GB:M13747 SP:P08178 PID:147425 GB:U00096 PID:1788845 percent identity: 76.30; identified by sequence similarity; putative
     
  0.900
nrfF
Formate-dependent nitrite reductase complex bifunctional subunit NrfFG; Possible subunit of a heme lyase
  
  
 0.660
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
  
 
 0.485
PGdx
Hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; In the C-terminal section; belongs to the glutaredoxin family
  
 
 0.469
HI_1452
Putative lysine exporter; Mediates export of lysine
       0.445
HI_1456
Uncharacterized protein HI_1456; Hypothetical protein; identified by GeneMark; putative
       0.405
HI_1457
Uncharacterized protein HI_1457; Similar to PID:2367659 percent identity: 34.32; identified by sequence similarity; putative; Belongs to the opacity porin family
       0.405
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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