STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
licBLic-1 operon protein (licB); Similar to GB:M27280 SP:P14182 percent identity: 99.01; identified by sequence similarity; putative. (292 aa)    
Predicted Functional Partners:
licA
Lic-1 operon protein (licA); Mediates phase variation of the LPS epitopes. Phase variation of H.influenza LPS epitopes expressed by LicA is determined by a translational switch (By similarity).
 
  
 0.976
licC
Lic-1 operon protein (licC); Similar to GB:M27280 SP:P14183 percent identity: 96.46; identified by sequence similarity; putative.
 
   
 0.974
licD
Lic-1 operon protein (licD); Transfers phosphorylcholine (ChoP) from choline diphosphonucleoside to the lipopolysaccharide (LPS). Belongs to the LicD transferase family.
 
   
 0.961
HI_1054
Conserved hypothetical protein; Similar to PID:1381738 percent identity: 92.49; identified by sequence similarity; putative.
  
     0.762
HI_1058
Predicted coding region HI1058; Hypothetical protein; identified by GeneMark; putative.
  
     0.753
HI_1055
Predicted coding region HI1055; Hypothetical protein; identified by GeneMark; putative.
  
     0.732
iga
Immunoglobin A1 protease (iga1); Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
  
     0.723
HI_1599
Predicted coding region HI1599; Hypothetical protein; identified by GeneMark; putative.
  
     0.610
tbpA
Transferrin-binding protein 1 precursor (tbp1); Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family.
  
     0.562
hindVRP
Type II restriction enzyme, putative; Similar to SP:P25261 SP:P24599 PID:43474 percent identity: 43.56; identified by sequence similarity; putative.
  
    0.522
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.