node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_1656 | HI_1657 | HI_1656 | HI_1657 | Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family. | Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfamily. | 0.787 |
HI_1656 | lpoA | HI_1656 | HI_1655 | Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family. | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.830 |
HI_1657 | HI_1656 | HI_1657 | HI_1656 | Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfamily. | Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family. | 0.787 |
HI_1657 | lpoA | HI_1657 | HI_1655 | Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfamily. | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.784 |
hemY | lolB | HI_0602 | HI_1607 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.705 |
hemY | lpoA | HI_0602 | HI_1655 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.718 |
hemY | matP | HI_0602 | HI_1323 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.672 |
hemY | recX | HI_0602 | HI_0599 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | Regulatory protein (recX); Modulates RecA activity; Belongs to the RecX family. | 0.462 |
hemY | trpR | HI_0602 | HI_0830 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | Trp operon repressor (trpR); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity). | 0.677 |
hemY | zipA | HI_0602 | HI_1101 | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | Cell division protein ZipA, putative; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.618 |
lolB | hemY | HI_1607 | HI_0602 | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | 0.705 |
lolB | lpoA | HI_1607 | HI_1655 | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.685 |
lolB | trpR | HI_1607 | HI_0830 | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Trp operon repressor (trpR); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity). | 0.496 |
lolB | zipA | HI_1607 | HI_1101 | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Cell division protein ZipA, putative; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.478 |
lpoA | HI_1656 | HI_1655 | HI_1656 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family. | 0.830 |
lpoA | HI_1657 | HI_1655 | HI_1657 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfamily. | 0.784 |
lpoA | hemY | HI_1655 | HI_0602 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | hemY protein (hemY); Involved in a late step of protoheme IX synthesis. | 0.718 |
lpoA | lolB | HI_1655 | HI_1607 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.685 |
lpoA | matP | HI_1655 | HI_1323 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.649 |
lpoA | mrcA | HI_1655 | HI_0440 | Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | Penicillin-binding protein 1A (ponA); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.934 |