STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL010759AAEL010759-PA. (526 aa)    
Predicted Functional Partners:
AAEL006107
Checkpoint protein; Belongs to the HUS1 family.
    
 0.999
AAEL009701
AAEL009701-PA.
    
 0.998
AAEL007649
Cell cycle checkpoint protein rad17.
   
 0.997
AAEL006788
Replication factor C.
   
 0.987
AAEL013962
AAEL013962-PA.
    
 0.985
AAEL007581
AAEL007581-PA.
   
 0.981
AAEL009465
AAEL009465-PA.
   
 0.975
AAEL003152
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.975
AAEL012826
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.954
AAEL014900
AAEL014900-PA; Belongs to the PI3/PI4-kinase family.
    
 0.947
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.