STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL004699AAEL004699-PA. (1006 aa)    
Predicted Functional Partners:
AAEL004317
AAEL004317-PA.
    
 0.781
AAEL003670
AAEL003670-PA.
   
 0.677
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
   
 0.629
AAEL014959
Heterogeneous nuclear ribonucleoprotein k.
   
 0.627
AAEL010340
Serine/arginine rich splicing factor.
   
 0.621
AAEL009659
Heterogeneous nuclear ribonucleoprotein l (hnrnp l).
   
 0.609
AAEL013723
Polypyrimidine tract binding protein.
   
 0.604
AAEL011568
AAEL011568-PA.
   
 0.598
AAEL006473
AAEL006473-PA.
   
 0.589
AAEL008755
AAEL008755-PA.
    
  0.564
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.