STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL011998AAEL011998-PA. (526 aa)    
Predicted Functional Partners:
AAEL004431
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.925
AAEL013891
Type i inositol-1,4,5-trisphosphate 5-phosphatase.
     
 0.919
AAEL010124
Phosphoinositide phospholipase C.
     
 0.916
AAEL011421
AAEL011421-PA; Belongs to the histidine acid phosphatase family.
     
  0.908
AAEL014842
AAEL014842-PA; Belongs to the histidine acid phosphatase family.
     
  0.908
AAEL011510
AAEL011510-PA; Belongs to the histidine acid phosphatase family.
     
  0.908
AAEL002846
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.906
AAEL010766
Kinase; Belongs to the inositol phosphokinase (IPK) family.
 
   
  0.900
AAEL009380
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.900
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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