STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL010854Ubiquitin carboxyl-terminal hydrolase. (934 aa)    
Predicted Functional Partners:
AAEL002240
AAEL002240-PA.
    
 0.850
AAEL008184
AAEL008184-PA.
    
 0.832
Ub52
Ubiquitin-52-amino-acid fusion protein.
   
 0.785
AAEL003877
AAEL003877-PA.
   
 0.709
AAEL003888
AAEL003888-PA.
   
 0.709
AAEL000795
AAEL000795-PA.
   
 0.709
AAEL008088
AAEL008088-PA.
   
 0.657
AAEL005339
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
   
 0.657
AAEL007205
Gata-binding factor-c (transcription factor gata-c).
    
 0.617
AAEL006119
AAEL006119-PA.
    
 0.617
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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