STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL002903Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1055 aa)    
Predicted Functional Partners:
AAEL013596
Phosphatidylinositol 3-kinase regulatory subunit.
    
 0.999
AAEL012071
AAEL012071-PA.
    
 0.987
AAEL001664
AAEL001664-PA.
    
 0.955
AAEL000693
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
0.953
AAEL004431
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.949
AAEL010238
Phosphatidylinositol-4-phosphate 5-kinase type i.
     
 0.927
AAEL008823
Non-specific serine/threonine protein kinase.
    
 0.909
AAEL009380
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.907
AAEL011417
AAEL011417-PA.
   
 
 0.905
AAEL003143
AAEL003143-PA.
   
 
 0.905
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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