STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL000149Histone deacetylase complex subunit SAP30 homolog; Required for the function of the class 1 Sin3-histone deacetylase complex (HDAC). (173 aa)    
Predicted Functional Partners:
AAEL002084
Suppressor of defective silencing.
   
 0.925
AAEL014016
AAEL014016-PA.
   
 0.896
AAEL009882
Retinoblastoma-binding protein 4 (rbbp4).
    
 0.890
AAEL014368
Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins.
     
 0.882
AAEL014711
AAEL014711-PA.
    
 0.854
AAEL014491
AAEL014491-PB.
    
 0.854
AAEL004586
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.836
AAEL001069
Histone deacetylase.
    
 0.796
AAEL002772
AAEL002772-PA.
    
 0.743
AAEL010054
AAEL010054-PA.
    
 0.709
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.