STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A7UVD2_ANOGAAGAP012222-PA. (70 aa)    
Predicted Functional Partners:
A7UV36_ANOGA
AGAP009664-PA.
   
 0.829
A0NFH8_ANOGA
AGAP004734-PA.
    
 0.790
Q7PVB4_ANOGA
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.670
A0A1W5C8V2
AGAP012211-PA.
   
 0.616
A0A1W5C9B1
AGAP012210-PA.
   
 0.616
A0NGF9_ANOGA
AGAP012209-PA.
   
 0.616
Q7PQN6_ANOGA
Nuclear receptor subfamily 1 group I.
   
 0.616
A7UUW6_ANOGA
AGAP004732-PA.
    
 0.610
Q7Q3B8_ANOGA
AGAP007801-PA.
   
 0.531
Q7PRV6_ANOGA
AGAP000029-PA.
    
 0.488
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.