STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QEU8_ANOGAHistone arginine demethylase. (426 aa)    
Predicted Functional Partners:
F5HKL1_ANOGA
AGAP002807-PB.
    
 
 0.746
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.710
Q7QD20_ANOGA
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.592
A0NDZ9_ANOGA
AGAP010554-PA.
      
 0.515
Q5TQ82_ANOGA
AGAP008505-PA.
      
 0.495
Q7PPV0_ANOGA
Histone demethylase JARID1.
      
 0.495
A0NBM1_ANOGA
AGAP006921-PA.
      
 0.493
Q7QG48_ANOGA
AGAP009499-PA.
    
 
 0.474
A7UUW9_ANOGA
Transcription elongation regulator 1.
 
    
 0.436
Q7PX54_ANOGA
AGAP001222-PA.
      
 0.410
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.