STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D1.1Actin, cytoplasmic. (376 aa)    
Predicted Functional Partners:
A0NGL9_ANOGA
AGAP012056-PA; Belongs to the actin-binding proteins ADF family.
   
 
 0.927
Q5TP19_ANOGA
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.838
Cdc42
Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
   
 0.802
Q7QJI4_ANOGA
AGAP007532-PA.
    
 0.778
Moe
Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane.
    
 
 0.774
Q7QH58_ANOGA
AGAP004071-PA.
   
 
 0.752
F5HL97_ANOGA
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.740
Q7PT29_ANOGA
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.740
Q7PJV2_ANOGA
AGAP010147-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.735
Q7Q1T1_ANOGA
AGAP009643-PA.
     
 0.720
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.